Microorganisms are prolific producers of secondary metabolites (natural products) that are not essential for life but offer a competitive advantage to the producing organism by acting as virulence factors, signaling molecules, or inhibiting the growth of other organisms. These biologically active molecules are also a significant source of pharmaceuticals, agrochemicals, cosmetics, and biofuels. However, the natural product of interest may not be produced in high quantities or may need to be modified before it commercially useful. The Skellam lab is seeking a Postdoctoral Research Associate in the field of natural product biosynthesis to elucidate and engineer microbial megasynthases and their associated biosynthetic pathways for biotechnological applications. Techniques we use include gene inactivation, gene cloning and expression, heterologous expression, combinatorial biosynthesis, small molecule purification and structural elucidation, and organic synthesis.