POSTDOC research opportunities are available immediately to explore the mechanisms of cell signaling and metabolic alterations in cancer. Our research focuses on understanding how mortalin/HSPA9 facilitates tumor cell proliferation and survival, especially in tumors driven by aberrant MEK/ERK activity. For example, we recently demonstrated that MEK/ERK deregulation puts tumor cells at risk of mitochondrial cell death, but mortalin can counteract this risk (PMID: 32156782; PMID: 32291414). Current projects investigate the molecular mechanisms underlying these processes, specifically focusing on the nature of mitochondrial stress and its impact on tumor cell metabolism. Postdoctoral research projects will stem from these findings and will also evaluate the potential of this stress to be exploited for tumor suppression. More about our ongoing research is available at https://www.mcw.edu/departments/biochemistry/faculty/jong-in-park-phd.
Prior experiences in cell signaling and metabolism using molecular/cellular biology and biochemistry techniques and Omics are desired, although not necessary. Experiences with cancer cell biological studies using cell lines and murine xenograft models will also fit well. If interested, please send curriculum vitae, a cover letter describing research interests, and contact information of three references to email@example.com.