Chemistry - General Biology - Cell Biology Biology - Biochemistry Sciences - General
The Scientific Director will be a key member of SMART-CAMP (Critical Analytics for Manufacturing Personalized-medicine) interdisciplinary research programme addressing key technology bottlenecks in cell therapy manufacturing: (i) critical quality attributes of safe, effective cell therapy products and (ii) integrated process analytics to monitor and modulate those attributes. While cell therapies are poised to transform healthcare for both the industry and the patient, there remain many outstanding scientific and technical challenges to make significant global impact that this R&D programme addresses. This high-impact focus includes measurement and feedback control of processing parameters that contribute to cell viability and function during cell proliferation, and the measurement at intermediate and final steps of the cell product properties correlated with positive therapeutic outcomes.
This CAMP interdisciplinary team comprises engineers, biologists, clinicians, and manufacturing experts from multiple MIT academic units, and multiple Singapore-based universities, research centers, and hospitals who are experienced at translational demonstrations of technologies in safety-regulated industries such as cell therapies. Our unique, enabling and cross-cutting capabilities include cell and clinical biology, microfluidics, real-time optics and spectroscopies, 3D-printed devices, process analytics, data analytics, and bioinformatics. This CAMP programme will demonstrate these approaches required of cell-based personalized medicine through three translational testbeds (three Flagship Projects), ultimately facilitating access for more patients to life-saving, approved cell therapies for currently intractable health challenges
SMART-CAMP seeks a Scientific Director with experience and expertise in cell therapy manufacturing. She or he will:
Assist the Co-Lead Principal Investigators of the CAMP program to support a team of investigators in executing technical scope and milestones of the program;
Participate in a Council of co-investigators who will set scientific operation milestones and internal operation policies of an interdisciplinary research team and programme;
Manage internal (within CAMP Interdisciplinary Research Group) and external communications;
Support external partnerships and collaborations with clinical, industrial, and regulatory stakeholders;
Act as technical expert within the wider clinical and cell therapy production / commercialization landscape in Singapore and facilitate team awareness on potential opportunities, complementary efforts by other R&D teams, and emerging production challenges in industry and clinical settings;
Act as a subject matter expert and provide consistent co-mentorship to postdoctoral and graduate student researchers in the CAMP program;
Represent the research programme at meetings with governmental agencies, industry sponsors, or visitors;
Oversee financial administration of the program; and
Perform other related duties as required.
Ph.D. in Biology, Chemistry, Biological Engineering, Chemical Engineering, Cell Biology, or Biophysics;
Biopharmaceutical experience, particularly with experience in industry, clinical, and/or manufacturing settings;
At least 3 years’ experience in research management in a medium/large scale research center or industry;
Demonstrated ability to build strategic collaborations to strengthen and enhance the research projects;
Proven ability to manage complex, multi-stakeholder programs;
Excellent written / verbal communication skills; and
MIT alumnus/alumna or previous MIT or SMART research appointment preferred.
To apply, please visit our website at: https://smart.mit.edu/careers/career-opportunities. Interested applicants are invited to submit their full CV (including papers published, patents filed, etc.), a cover letter, a research leadership statement (2 pages), and list of three references (to include reference names and contact information). We regret that only shortlisted candidates will be notified.
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