The constant search for new chemical entities for the treatment of diseases necessitates the development of chemical synthesis methods that can rapidly access derivatives of complex small molecule structures.
Research in the group is centered on developing new molecular editing strategies with transition-metal complexes and organocatalysts. More specifically, the group is interested in 1) functional group editing by enabling methylene-heteroatom exchanges to modify hydrocarbon frameworks; and 2) scaffold editing by designing new organocataysts for product-selective transformations from a common intermediate to access topologically complex natural product-like scaffolds.
