The Koren lab is a multidisciplinary group that integrates biochemistry, molecular biology, and biophysics to study diseases of protein aggregation, neurodegeneration, and cancer. Primarily, our work focuses on the activity and regulation of molecular chaperones. Molecular chaperones are the quality control system of living cells. Dysregulation or aberrant activity of molecular chaperones can drive the underlying pathology in diseases such as Alzheimerâs disease, post-traumatic stress disorder, glaucoma, and cancer.