Who's Who in
Sciences Academia

    James Van Brocklyn

  • Assistant Professor
  • James Van Brocklyn
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  • Department of Biological Sciences
  • http://www.biosci.ohiou.edu/
  • Ohio University
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  • Irvine Hall
    Athens, Ohio 45701
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  • Contact by e-mail?
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  • My research interests include signal transduction mechanisms mediated by sphingolipids and the roles they play in cancer. As a graduate student I investigated the role of gangliosides, sialic acid-containing glycosphingolipids, in the brain tumors. Expression of certain types of gangliosides correlates with the malignancy of some brain tumors. I showed that gangliosides regulate the activity of growth factor receptor tyrosine kinases. Thus changes in ganglioside expression can cause more aggressive growth brain tumors.
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