* Ontogenic and functional heterogeneity of macrophage populations.
* Macrophage-mediated regulation of innate and acquired immune responses.
* Phagocytosis-mediated immunoregulations: Intracellular trafficking of particles and activation of cellular signaling.
* Development of a new Th1 adjuvant, beneficial against intracellular bacterial infections as well as childhood asthma.
* Mechanisms of Th1-to-Th2 shifts of immune responses in chronic inflammatory cardiovascular diseases.