Prof. Makowski's research focus is on the development and use of innovative biophysical methods for the study of complex biomolecular systems. His current research interests include use of x-ray solution scattering and neutron spin-echo spectroscopy for the study of proteins in solution including characterization of protein-protein and protein-ligand interactions and structural fluctuations; the use of coherent diffraction imaging for the study of crystalline fibrils in complex biological tissues, with particular emphasis of cellulose in plant cell walls.