Intelligent computing: computer vision, pattern recognition, machine learning, artificial intelligence and data mining. He has been active in the research fields of medical image analysis, statistical data analysis, cognitive vision and face recognition. His earlier work on face recognition has produced a winning system in the well-known FERET competition, setting the industry-standard. His recent work on lung tumor segmentation and detection in chest CT scans has resulted in a number of US, German, Chinese and Japanese patents.