Our laboratory studies protein synthesis in all three domains of life. Studies encompass detailed mechanistic investigations by enzymology and Xray crystallography, bioinformatics-aided gene discovery, and molecular genetics approaches in methanogenic Archaea. Our laboratory includes equilibrium and stopped-flow fluorescence instruments, a rapid chemical quench kinetics apparatus, and automated robotics for high-throughput crystallization. An OHSU affiliation enables access to Xray diffraction equipment and to a high-energy synchrotron beamline.