Prof. Sazinsky's research activities employ X-ray crystallography and biochemical techniques as primary tools to answer important questions about the structure and function of proteins. The major research themes are to identify the determinants of metalloenzyme activity and tuning, re-engineer proteins for altered functions and/or expanded catalytic capabilities, and to provide a basis for understanding the biochemical processes in pathogenic bacteria. Undergraduate research students are heavily involved in the structural and biochemical characterization of specific protein targets.
