There is one goal--deconstructing the human heart – using computer-based X-ray micro and nano tomographic techniques.
This involves minimally intrusive sequential analysis of the intact heart with CT methodology that yields micrometer dimensional isotropic voxels followed by large to small sector sub-analysis yielding nanometer dimensional voxels. The end results are coherent natural-context data sets that can be examined and measured in 3D space with differing degrees of magnified detail. From the cellular level to the multi-cellular fascicular level and beyond, the fabric of the heart wall’s construction can be visualized. This structural detail not only underlies the complex biomechanical activity of the heart but is critical to understanding the spread of electrical activation in the heart wall. Such an isotropic voxel information data base for the human or any heart does not exist at this time but is now in the process of incremental creation in the human heart.
