We use techniques in biochemistry, electrochemistry and microbial ecology to characterize the biochemistry of microbes that inhabit a wide range of geologic features (including subsurface hydrothermal and petroleum systems, hydrothermal mud volcanoes, hydrothermal vents, acidic hot springs and aquatic and marine sediments). We are specifically interested in the systems used by these organisms in electron-transfer reactions. These reactions can provide the driving force for the life of the organism, be used to maintain an internal “balance” of oxidizing and reducing compounds, or protect against oxidative and other stresses. Many geologically important reactions are controlled by this biochemistry, and we are specifically interested in sulfur-based respiration and the role that microbes play in the sulfur cycle and in the formation and breakdown of sulfur-containing compounds and minerals