1. Understanding the interaction between cytoskeletal proteins and second messengers.
2. Structure-function studies examining the role of post-translational modification of actin regulatory proteins and microfilament organization.
3. Regulation of epithelial cell structure and function by microfilaments.
4. Regualtion of cell motility including epithelial-mesenchymal transition by actin-binding proteins and microfilament organization.
5. Regulation of cell death (apoptosis and autophagy) by actin-binding proteins.