Thrombosis or clotting, is the cause of 50% of deaths in North America. However, blood coagulation is essential in arresting hemorrhaging. Thus, there must be a delicate balance betwen these processes. When this balance is disturbed, patients suffer from hemphilia, strokes, heart attacks and cardiovascular disease. Heparin, a negatively charged polysaccharide, is a potent anticoagulant which ihnhibits blood clotting. The protein platelet factor 4 plays a key role in blood coagulation
