Dr. Riley's research is all based on computational chemistry techniques and is mainly focused on the treatment of noncovalent interactions. Noncovalent interactions play critical roles throughout Chemistry and are extremely important in protein structure, the interactions of ligands with proteins, material science, and fluid dynamics. The main focus of Dr. Riley's research is in the application of computational methods to treat noncovalent interactions in biological systems, including nucleic acids (DNA/RNA), proteins, and (especially) protein-ligand complexes. Dr. Riley is particularly interested in halogen bonds and the roles that they play in protein-ligand bonding.