This genetic variation can be in the form of polymorphisms in coding regions, non-coding regions and regulatory elements, and copy number variation. Genetic variations in transcription factors and their binding sites can change gene regulatory networks allowing rapid adaption to new environments and provides insights into molecular mechanisms of these pathways. These changes in gene regulatory networks alter transcription and the cellular proteome, ultimately impacting an organism’s response to stresses and disease. Future experiments will explore how different chemicals such as chemotherapeutic drugs, hydrocarbons from mining and food additives affect cellular pathways. My lab uses high throughput genomics, transcriptomics and proteomics to address the impact of genetic diversity on cellular mechanisms within a species
