My research group utilizes quantitative fluorescence microscopy techniques to investigate biophysical and biochemical interactions in single cells. A complete understanding of molecular interactions inside cells (proteins, ligands, lipids, RNA, DNA, etc.) greatly increases our knowledge of how cells function. Fluorescence imaging is a powerful analytical tool that makes it possible to investigate molecular interactions in the physiological conditions of intact cells. We apply these methods to understand both intracellular dynamics and the effects cell-to-cell variation has on a population’s response to change.
