Who's Who in
Sciences Academia

    Jay Brenman

  • Professor
  • Jay Brenman
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  • Department of Cell and Molecular Physiology
  • http://www.med.unc.edu/dept_cmphysiology.htm
  • University of North Carolina, Chapel Hill
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  • 51 Medical Sciences Research Building CB# 7545
    Chapel Hill, North Carolina 27599-7545
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  • Contact by e-mail?
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  • All cells and organisms must monitor and maintain their energy levels for survival. One particular protein kinase, AMP-activated protein kinase (AMPK) plays a central role in energy balance and metabolism. AMPK consists of a protein complex encoded by three subunits, a serine-threonine kinase catalytic subunit (α) and two regulatory subunits (ß, γ). When AMPK signaling is disrupted cells undergo cell death under stressors and organisms can not survive limited starvation.
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