Yingcui Li's research is on genes and development. As a developmental biologist and cartilage biologist, her research has been focused on function of Hyaluronan, a large molecular made by cartilage cells, for limb and synovial joint development. Recently, she has developed transgenic mouse models for the genetic analysis of Hyaluronan function in Osteoarthritis. The general goal of her research is to provide insight into new targets and reveal new approaches for Osteoarthritis treatment, including novel drug target or gene therapy.