Our research focuses on the development of new methods for the syntheses of architecturally complex natural products. This encompasses the development of new methods for the fluorination of alkyl and aryl radicals, the use of oxygen- and nitrogen-centered radicals for the synthesis of heterocycles, organometallic reagents for the development of new bond construction techniques, the enantioselective synthesis of building blocks for total synthesis, and the development and evaluation of proposed biogenetic pathways through biomimetic synthesis. Central to efficient methods development is a fundamental understanding of reactivity and reaction mechanisms.
